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You may see your pimples obtaining even worse at first - yet this is normal, and it implies Accutane is working right. See to it you take it twice a day regarding meals unless your wellness treatment provider advised doing or else. Any kind of medicines you are making use of have to be reported before you begin taking Accutane, especially any of the following ones: oxytetracycline, vitamin A supplements, doxycycline, phenytoin, prednisone, tetracycline, minocycline, demeclocycline, dexamethasone, or methylprednisolone.